Curated and harmonised transcriptomics datasets of interstitial lung disease patients

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Inkala, S., Federico, A., Serra, A., & Greco, D. (2024). Curated and harmonised transcriptomics datasets of interstitial lung disease patients [Dataset]. Zenodo. https://doi.org/10.5281/ZENODO.10692129

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The datasets uploaded within this record contain transcriptomics data of interstitial lung disease patients retrieved from the NCBI Gene Expression Omnibus and European Nucleotide Archive (ENA) repositories. Overall, we retrieved 30 transcriptomics datasets, produced through both DNA microarrays and RNA-Sequencing technologies, along with relative meta-data tables. After data collection, all the datasets underwent meta-data curation and harmonisation, data quality check, and pre-processing with standardised procedures. Beside, data model was created in order to homogenise the phenotypic data enabling the comparability across the datasets. In addition, for every study included in this data release we provide tables of differentially expressed genes and co-expression network models of IPF samples and healthy counterparts deriving from both RNA-seq and DNA microarrays.

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transcriptomics, DNA microarray, RNA sequencing, systems biology, interstitial lung disease, idiopathic pulmonary fibrosis

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